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Hiroshi Takahashi Selected Research

SI 27

5/2004Inhibition of glioma angiogenesis and invasion by SI-27, an anti-matrix metalloproteinase agent in a rat brain tumor model.
1/2004Drug-induced apoptosis by a matrix metalloproteinase inhibitor, SI-27 on human malignant glioma cell lines; in vitro study.
1/2003Anti-invasive effect of an anti-matrix metalloproteinase agent in a murine brain slice model using the serial monitoring of green fluorescent protein-labeled glioma cells.
5/2002Suppression of matrix metalloproteinase activity by SI-27: detection by a new activity assay with S-2444, a specific chromogenic peptide.
1/2002Tracking cell invasion of human glioma cells and suppression by anti-matrix metalloproteinase agent in rodent brain-slice model.

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Hiroshi Takahashi Research Topics

Disease

48Neoplasms (Cancer)
04/2022 - 01/2002
18Inflammation (Inflammations)
01/2022 - 05/2002
17Infections
05/2022 - 01/2005
16Coronary Artery Disease (Coronary Atherosclerosis)
10/2022 - 08/2003
15Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 12/2004
15Glioma (Gliomas)
09/2011 - 01/2002
14Pain (Aches)
05/2022 - 01/2004
14Rheumatoid Arthritis
12/2021 - 01/2004
13Burns
01/2021 - 01/2007
12Cataract (Cataracts)
01/2021 - 02/2005
12Myocardial Infarction
01/2021 - 06/2002
10Chronic Renal Insufficiency
11/2022 - 01/2011
9Pneumonia (Pneumonitis)
03/2021 - 07/2004
9Chronic Kidney Failure (Chronic Renal Failure)
02/2020 - 01/2007
9Stomach Neoplasms (Stomach Cancer)
02/2016 - 11/2002
9Carcinoma (Carcinomatosis)
06/2013 - 01/2003
8Low Back Pain (Lumbago)
02/2022 - 09/2012
8Peripheral Arterial Disease
01/2022 - 06/2007
8Spinal Cord Injuries (Spinal Cord Injury)
12/2021 - 03/2012
7Pathologic Constriction (Stenosis)
01/2022 - 01/2010
7Body Weight (Weight, Body)
01/2021 - 08/2002
7Type 2 Diabetes Mellitus (MODY)
11/2020 - 01/2016
7Spinal Cord Diseases
04/2020 - 11/2009
7Brain Neoplasms (Brain Tumor)
07/2012 - 11/2002
6Hepatocellular Carcinoma (Hepatoma)
08/2022 - 12/2003
6Heart Failure
08/2021 - 02/2003
6Wounds and Injuries (Trauma)
06/2021 - 02/2005
6Ischemia
10/2020 - 06/2005
6Communicable Diseases (Infectious Diseases)
09/2020 - 06/2002
6Neoplasm Metastasis (Metastasis)
01/2020 - 05/2007
5Stroke (Strokes)
03/2022 - 05/2013
5Fibrosis (Cirrhosis)
01/2022 - 06/2007
5Intervertebral Disc Displacement (Herniated Disc)
01/2022 - 07/2014
5Sepsis (Septicemia)
08/2021 - 12/2016
5Hemorrhage
05/2021 - 06/2003
5Adenoma (Adenomas)
03/2021 - 03/2003
5Hypoglycemia (Reactive Hypoglycemia)
03/2021 - 12/2016
5Atherosclerosis
01/2020 - 01/2008
5Alzheimer Disease (Alzheimer's Disease)
11/2015 - 07/2007
4Osteoporosis
07/2022 - 03/2008
4Paralysis (Palsy)
03/2022 - 10/2010
4Surgical Wound Infection
12/2021 - 03/2016
4Respiratory Insufficiency (Respiratory Failure)
03/2021 - 01/2005
4Muscle Spasticity (Spastic)
05/2020 - 07/2008
4Human Influenza (Influenza)
09/2016 - 08/2013
4Parkinson Disease (Parkinson's Disease)
01/2013 - 10/2002

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
05/2022 - 11/2002
12AlkaliesIBA
01/2021 - 01/2007
11Pharmaceutical PreparationsIBA
01/2022 - 06/2002
11Retinaldehyde (Retinal)IBA
01/2021 - 09/2009
11Messenger RNA (mRNA)IBA
01/2021 - 04/2002
10CytokinesIBA
02/2022 - 09/2005
9Granulocyte Colony-Stimulating Factor (G-CSF)IBA
12/2021 - 03/2012
9Ophthalmic Solutions (Eye Drops)IBA
11/2021 - 01/2010
9Biomarkers (Surrogate Marker)IBA
03/2021 - 06/2003
8Anti-Bacterial Agents (Antibiotics)IBA
05/2022 - 01/2005
8Glucose (Dextrose)FDA LinkGeneric
03/2021 - 10/2016
8C-Reactive ProteinIBA
01/2021 - 12/2009
8AntigensIBA
09/2016 - 06/2002
7EnzymesIBA
01/2020 - 10/2002
7Serum AlbuminIBA
08/2017 - 12/2010
7Matrix Metalloproteinases (MMPs)IBA
01/2007 - 01/2002
5Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2022 - 07/2008
5AntibodiesIBA
01/2021 - 02/2004
5Biological ProductsIBA
11/2019 - 01/2016
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2017 - 02/2008
5SI 27IBA
05/2004 - 01/2002
4LipidsIBA
10/2022 - 12/2010
4Phenobarbital (Luminal)FDA Link
01/2022 - 01/2010
4Therapeutic UsesIBA
06/2021 - 04/2004
4Hemoglobins (Hemoglobin)IBA
03/2021 - 01/2015
4AlbuminsIBA
03/2021 - 01/2015
4insulin degludecIBA
03/2021 - 10/2016
4Monoclonal AntibodiesIBA
01/2021 - 02/2004
4omega-Chloroacetophenone (Mace)IBA
01/2021 - 01/2014
4InterferonsIBA
11/2020 - 05/2009
4Adrenal Cortex Hormones (Corticosteroids)IBA
10/2020 - 01/2011
4CreatinineIBA
02/2020 - 01/2015
4oxidized low density lipoproteinIBA
11/2018 - 06/2009
4CaspasesIBA
07/2018 - 12/2003
4Carboplatin (JM8)FDA LinkGeneric
01/2018 - 10/2002
4CarbohydratesIBA
01/2016 - 01/2008
4ErbB Receptors (EGF Receptor)IBA
07/2012 - 01/2002

Therapy/Procedure

63Therapeutics
10/2022 - 01/2002
33Renal Dialysis (Hemodialysis)
01/2022 - 08/2003
22Drug Therapy (Chemotherapy)
04/2022 - 10/2002
11Decompression
05/2022 - 09/2003
9Radiotherapy
11/2022 - 10/2002
9Lasers (Laser)
11/2021 - 01/2002
9Stents
12/2019 - 01/2008
8Phacoemulsification
01/2021 - 02/2005
8Percutaneous Coronary Intervention
01/2021 - 08/2006
7Activities of Daily Living (ADL)
03/2022 - 06/2005
6Conservative Treatment
01/2022 - 01/2013
5Laminectomy
01/2022 - 01/2019
5Spinal Fusion (Spondylosyndesis)
01/2022 - 10/2010
5Glycemic Control
05/2019 - 01/2016
5Gastrectomy
01/2016 - 03/2008
4Hematopoietic Stem Cell Transplantation
11/2019 - 12/2010
4Semiconductor Lasers
01/2014 - 01/2003